| EPDM | Excellent resistance to weather, ozone, and water; good flexibility | Poor resistance to oils, fuels, and solvents | Water, steam, glycol fluids | Mild acids and bases | Oils, hydrocarbons, strong solvents |
| Neoprene | Good balance of chemical and weather resistance; flame resistant | Limited resistance to strong acids and hydrocarbons | Refrigerants, water, moderate chemicals | Light oils, diluted acids | Aromatic hydrocarbons, strong oxidizing acids |
| Nitrile (Buna-N) | Excellent oil and fuel resistance; good abrasion resistance | Poor weather, ozone, and UV resistance | Petroleum oils, fuels, lubricants | Water, glycols | Strong acids, ozone, sunlight |
| TPE (Thermoplastic Elastomer) | Flexible, recyclable, easy to process | Lower heat and chemical resistance than thermoset rubbers | Water, mild chemicals | Light oils, cleaning agents | Strong solvents, fuels, high heat |
| SBR (Styrene-Butadiene Rubber) | Good abrasion resistance; cost-effective | Poor resistance to oils, ozone, and weathering | Water, alcohols | Weak acids and bases | Oils, fuels, ozone |
| Silicone | Excellent high/low temperature resistance; good weathering and flexibility | Poor abrasion, tear strength, and low fuel/oil resistance | Air, ozone, water, dry heat | Mild chemicals | Petroleum oils, fuels, concentrated acids |
| Butyl | Excellent gas and air impermeability; good resistance to acids | Poor resistance to oils and fuels | Water, acids, alkalis | Alcohols, ketones | Petroleum oils, fuels, solvents |
| Viton (FKM) | Excellent chemical, oil, and heat resistance | Limited flexibility at low temperatures; high cost | Oils, fuels, solvents, acids | Steam, hot water | Low-temperature environments, ketones |
| Polyurethane | Outstanding abrasion and tear resistance; good load-bearing | Poor resistance to water, heat, and some solvents | Oils, fuels, greases | Alcohols, mild chemicals | Hot water, steam, acids |
| Fluorosilicone | Excellent fuel and oil resistance with wide temperature range | Lower mechanical strength and tear resistance; costly | Fuels, oils, solvents | Mild chemicals, dry heat | Strong acids, bases, steam |
